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MS402 is a small-molecule, BD1-selective inhibitor of BET bromodomains used in preclinical research to modulate BET-mediated transcription and Th17-driven inflammatory responses.
Selective BD1 bromodomain inhibition.
Reported Ki values for BET bromodomains, e.g., BRD4(BD1) 77 nM, BRD4(BD2) 718 nM.
Demonstrated activity blocking Th17 cell differentiation and ameliorating colitis in mice.
Purity 98.36% and molecular weight 370.83 g/mol.
Molecular formula C20H19ClN2O3.
Intended for laboratory research use only; not for human use.
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TO-1187 TFA is a selective HDAC6 PROTAC degrader with a DC50 of 5.81 nM. It promotes the ubiquitination and degradation of HDAC6 and is used in the study of hematological malignancies and solid tumors. The compound is composed of an HDAC6 ligand, a CRBN ligase ligand, and a linker.
Selective PROTAC degrader
Promotes ubiquitination and degradation of HDAC6
Applicable for studying hematological malignancies and solid tumors
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If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link: eMolecules Building Block Tool<|a>
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Hexamethylene bisacetamide (HMBA) is a research reagent used to induce cell differentiation and to study apoptosis and related signaling pathways. It is supplied as a solid and as DMSO solutions for in vitro laboratory applications, and is offered in multiple pack sizes for different experimental scales.
Induces cell differentiation in multiple cell lines.
Used to study apoptosis and signaling pathways.
Supplied as a solid and as DMSO solutions for flexible use.
Available in multiple pack sizes to suit experimental scale.
High purity (99.6%) suitable for analytical and research use.
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Tetraethylammonium tetrafluoroborate is a quaternary ammonium salt (CAS 429-06-1) supplied as a solid reagent for research and synthesis. It is commonly used as a phase-transfer catalyst, an electrolyte in electrochemical applications, and as a source of tetraethylammonium ions in organic and biochemical experiments. Typical purity is ≥98.0% and molecular weight is 217.06 g/mol.
High purity suitable for research applications.
Useful as a phase-transfer catalyst in organic synthesis.
Functions as an electrolyte in electrochemical cells and studies.
Solid form with convenient laboratory handling and storage.
Provides a reliable source of tetraethylammonium ions for biochemical experiments.
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D13-9001 is a small-molecule inhibitor of bacterial efflux pump subunits AcrB and MexB, supplied for research applications to investigate efflux-mediated antibiotic resistance. The compound has a molecular formula of C31H39N11O6S, a molecular weight of 693.78, and is offered at high reported purity for in vitro studies.
Inhibits AcrB and MexB efflux pump subunits.
Supports studies of antibiotic resistance mechanisms.
High purity suitable for analytical and biological assays.
Molecular weight 693.78 and formula C31H39N11O6S.
Available in small-molecule pack sizes including 5 mg.
For research use only; not for human or clinical use.
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2-Aminoheptane (Tuaminoheptanez Tuamine Heptamine 1-Methylhexylamine 2-Heptylamine) is a nasal decongestant drug which is a sympathomimetic stimulant and vasoconstrictor
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